Materials

The following materials are available for the Syllego system:

Rosetta Syllego™ System Brochure

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Rosetta Syllego™ System FAQs

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Application of the Rosetta Syllego™ System in Genetic Data Management and Analysis

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Support

If you are a Syllego system customer, go to the Support area to access Syllego system support materials:

- Documentation
- Reference data
- Analysis workflows
- Software updates
- Known issues
- User forum

For an overview of available types of customer support, visit the Syllego system configurations page.

Rosetta Syllego System

What's New? | Features | More Information | Evaluate

The Rosetta Syllego™ Genetic Data Management and Analysis System is Rosetta's practical solution for scientists engaged in genetic studies such as genome-wide association, linkage, and eQTL studies.

The Rosetta Syllego™ system is designed to enable you to focus on what matters: the science behind your genetic study.

The system is a resource for managing genetic variation information and integrating relevant study data from various sources so that scientists and researchers can better plan and execute genetic studies.

Designed for biologists, statistical geneticists, and investigators responsible for generating genotyping data, the Syllego system provides you with an easy-to-use project workspace so that you can organize, analyze, and share your genotype and phenotype data along with your analysis results.

With the Syllego system, generating high quality analysis data and meaningful results becomes simple. The Syllego system automates all tedious data management and data formatting tasks so that you can streamline your genetic analysis workflows using your analysis methods of choice.

Managing all your genetic data and reference information is straightforward. The Syllego system converts public and private genotype data sets and reference annotations, such as dbSNP and HapMap, as well as individual (sample) information into a single, consistent repository for fast, convenient access.

What's New?

To review the list of new enhancements for the latest version of the Syllego system, download our PDF.

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Features

The following features are described below:

Project and Managment

  • Define the project organization of your study data, assay data, and analysis results.
  • Manage and analyze SNP genotyping data generated from multiple genotyping assay technologies, including Affymetrix® and Illumina®.
  • Gather and manage genotypic and phenotypic data from public resources such as the Coriell Institute of Medical Research's Q application or from your private systems.
  • Select genes, markers (SNPs), and individuals through a user-friendly interface. (Figure 1)
  • Interface with genotyping service providers such as Affymetrix, Illumina, Perlegen, and others.
  • Publish and share your genotype data, analysis results, and methods with collaborators.

 
Figure 1: You can easily combine various genotype data sets from different assays or different technologies into one single study data set for downstream analyses.
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Quality Control

  • Verify and correct SNP marker, individual (sample), and genotype data.
  • Execute semi-automated study data quality control checks. (Figure 2)
  • Generate data quality control reports and activity logs.
  • Integrate your quality control analyses into your analysis data set preparation.
  • Merge and subset data for comparison and validation against existing data sets.

 
Figure 2: Extensive quality control checks enable you to merge or subset relevant study data into analysis data sets targeted for further analysis.
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Analysis Tool Suite

  • Use the analysis method of your choice.
  • Add additional phenotype data to individuals (samples) stored in the system.
  • Generate analysis templates for shared analysis methodologies.
  • Integrate common statistical tools and genetic packages, such as R, PLINK, and Haploview applications.
  • Link, script, and schedule your analysis jobs.
  • View your analysis results directly through many integrated Syllego visualization tools. (Figure 3)
  • Use the genome viewer to determine the genomic context of your analysis results.

 
Figure 3: The Syllego analysis tool suite not only allows you to interface with the analysis method of your choice, but also view your analysis with Syllego visualization tools.  
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Data Management

  • Catalog your study data with your analysis results for use with future studies and collaboration efforts.
  • Store your study data in a common data repository and assign access controls.
  • Connect and merge public and private genetic data and results.
  • Configure links to the Web resources of your choice.
  • Manage multiple genome assemblies for Human, Mouse, and other species.
  • Report and publish analysis results and study outcome to collaborators. (Figure 4)
  • Automate data loading and merging of public data sets such as HapMap, genotype data from source providers, and in-house assay results.

 
Figure 4: The system enables you to assign data access controls for your project and to share your genetic data, analysis methods, and results with your colleagues and collaborators.
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More Information

For information about purchasing the Syllego system, please contact our Sales Team.

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